Is CBD effective without THC? According to many THC advocates or bud tenders you may speak to at your local dispensary, CBD needs to be activated by THC or it is only really effective if there's THC present in the tincture, edible or other delivery system you're using. Is this actually true? There are some people who have had life-changing improvements in quality of life from using CBD products alone, or from using THC products alone. Others claim that a combination of cannabinoids is the only way they find true relief. In this article, we explore why people may be having these different experiences - and how you can decide what the best options are for you.