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Is CBD Effective Without THC?

Is CBD Effective Without THC?

Is CBD effective without THC? According to many THC advocates or bud tenders you may speak to at your local dispensary, CBD needs to be activated by THC or it is only really effective if there’s THC present in the tincture, edible or other delivery system you’re using.

Is this actually true?

There are some people who have had life-changing improvements in quality of life from using CBD products alone, or from using THC products alone. Others claim that a combination of cannabinoids is the only way they find true relief. In this article, we explore why people may be having these different experiences – and how you can decide what the best options are for you.

How CBD Works Vs How THC Works

How CBD and THC work

What is known about CBD and THC is that both molecules act on totally different nerve receptors in totally different parts of the brain and the body.

Tetrahydrocannabinol, or THC, is psychoactive, and is identified by a different part of the brain than cannabidiol (or CBD) does. Both compounds interact with the endocannabinoid system, but on different endocannabinoid receptors.

Despite this, data does point to the existence of an “entourage effect” – essentially the idea that all of the cannabinoids and terpenes present in a specific strain amplify the therapeutic effects of the plant when consumed together. Read more about that HERE.

While the Entourage Effect is real, CBD on its own (for example, in isolate form) absolutely does have beneficial effects, without the need for THC. Currently, the only approved use of CBD by the Food and Drug Administration is in the form of Epidiolex, which is a pure CBD tincture prescribed to treat two specific types of juvenile epilepsy. 

Since the Farm Bill passed in 2018 allowing for nationwide distribution of CBD, many people have become more educated about hemp-derived CBD, and have learned that while CBD and THC are found in the same plants, these compounds do different things and have many different uses – but are also magical when used together.


Why Some May Believe That THC Is Needed For CBD To Work

To explore this topic further, let’s use pain relief as an example – one of several popular uses of cannabis. People take CBD for pain relief, and are known to consume marijuana for this purpose as well. That’s because they both absolutely work! Just in different ways. Consuming them together for pain may be extremely effective – but not necessary. We always recommend experimenting to learn what works best for your own body – everyone’s endocannabinoid system is different!

THC activates certain cannabinoid receptors, one of which is in the nerve cells and the other is in the immune cells. When it activates the receptors in the nerve cells, it reduces the sensation of pain. As an added benefit, the high or euphoria sometimes experienced by THC can help to numb the sensation of pain, or help with coping and pain tolerance.

On the other hand, CBD is a powerful inflammation fighter. Inflammation in our bodies is often a cause of musculoskeletal pain, so CBD offers relief. This can be experienced “full body” when ingested or vaped, or if you have an acute area of pain you can apply an extra strength CBD lotion (or THC lotion – or ratio!); because we have an endocannabinoid system in our skin, the cannabinoids can interact topically for relief. From the National Institute of Health: “Cannabinoids exert anti-inflammatory effects in skin, through both their actions on keratinocyte cytokine production and their modulation of immune cells.”

In summary, THC and CBD are both effective for pain in different ways, – and while they’re wonderful when used together, they can absolutely be used on their own as well. So if you don’t have access to a dispensary in your state, no need to fear! You can still find effective cannabis products online from CBD brands like TribeTokes that ship to all 50 states.

The science behind CBD’s therapeutic benefits

Let’s look at its potential therapeutic benefits to further understand CBD’s effectiveness without THC. CBD interacts with the endocannabinoid system, which regulates bodily functions such as appetite, sleep, and pain. (For sleep, also check out our CBN tincture, and for pain also check out our CBG tincture. The effects are shown once the cannabinoid interacts with CB1 and CB2 receptors, which reduces pain and inflammation.

The benefits of using CBD products without THC

There are many benefits of CBD products that are free from the psychoactive substance THC. Here are some of them:

  • No psychoactive effects: As mentioned above, CBD does not induce a feeling of “high” associated with THC use. This makes the cannabinoid a safe and effective alternative to THC.
  • Legal: CBD products are legal in most states as long as they are made from hemp (A cannabis plant with low levels of THC). 
  • Versatile: CBD products are available in various forms, like gummies, creams, and oils. This makes it easy for you to incorporate CBD into your daily routine.


CBD is still considered effective even if you use it without THC. Thus, whether you are looking to relieve pain, improve your sleep, reduce anxiety, or experience other therapeutic benefits of cannabinoids, you can still effectively and safely use CBD products that are free from THC. If you are interested in trying such CBD products, choose a reputable brand such as TribeTokes.

Frequently Asked Questions

Can CBD be effective without THC?

CBD can provide therapeutic benefits even without THC. This is because these two cannabinoids have distinct effects on the body. For example, THC is known to create a “high” and has psychoactive effects, while CBD does not cause these sensations. Research studies have demonstrated CBD’s potential to help with various medical conditions, including anxiety reduction, pain relief, and improved sleep. Although many CBD products do include THC, other products does not contain the psychoactive cannabinoid. CBD products without THC are especially relevant to those highly sensitive to THC’s impact or who must pass drug tests that detect THC.

What are the benefits of using CBD without THC?

The use of CBD without THC offers a bunch of benefits. Generally, CBD products provide therapeutic effects without the psychoactive properties associated with THC. This is great for those who are sensitive to the psychoactive effects of THC or prefer to avoid them altogether. CBD products with no THC are also suitable for those required to undergo drug tests that detect THC, especially if you are working in industries like transportation or healthcare.

Are there any potential side effects of using CBD without THC?

CBD is safe, but possible side effects could still occur. The most prevalent adverse effects include dry mouth, drowsiness, and changes in appetite or weight. CBD may also interact with other medications, so it is essential to consult a healthcare professional before combining it with other medicines.

It is also worth noting that the quality and purity of the CBD product can influence the potential side effects of CBD. Low-quality CBD products can contain hazardous substances or contaminants that could result in adverse effects. So, make sure to use quality, third-party tested CBD products from trustworthy brands.

How can I ensure that the CBD product I’m using is THC-free?

To ensure that the CBD product you are using does not contain THC, there are several steps you can take. First, carefully read the product label to see if it states that it is THC-free or contains 0% THC. Also, you can check the product’s certificate of analysis (COA), a third-party lab report that verifies the product’s contents, including the levels of CBD and THC. The COA should be available on the manufacturer’s website or by request.

Another way to ensure your CBD product is THC-free is to purchase products from reputable and trustworthy companies. Look for companies with good reputations and use third-party testing to verify the quality and contents of their products. 

Is using CBD products without THC legal in my state or country?

The legality of using CBD products without THC varies depending on the laws and regulations of your state or country. In the United States, CBD products made from hemp that contains less than 0.3% THC are legal under federal law.

Researching the laws in your state or country is essential to ensure that CBD products without THC are legal. Some states and countries may allow CBD products without THC for medical purposes, while others may restrict or prohibit their use.

It is also essential to keep in mind that the legal status of CBD products without THC can depend on the source of the product. For example, CBD derived from hemp is generally considered legal, while CBD derived from marijuana may be subject to more stringent regulations.

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